The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2012

Filed:

Jun. 26, 2008
Applicants:

Jonathan L. Haines, Nashville, TN (US);

Simon G. Gregory, Durham, NC (US);

Silke Schmidt, Durham, NC (US);

Margaret A. Pericak-vance, Coral Gables, FL (US);

Mariano Garcia-blanco, Durham, NC (US);

Inventors:

Jonathan L. Haines, Nashville, TN (US);

Simon G. Gregory, Durham, NC (US);

Silke Schmidt, Durham, NC (US);

Margaret A. Pericak-Vance, Coral Gables, FL (US);

Mariano Garcia-Blanco, Durham, NC (US);

Assignees:

Duke University, Durham, NC (US);

Vanderbilt University, Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides, in certain aspects, a method of identifying a subject as having an increased risk of developing multiple sclerosis, comprising detecting in the subject the presence of a nucleotide variant in the interleukin 7 receptor alpha chain gene, whereby the presence of said variant identifies the subject as having an increased risk of developing multiple sclerosis.


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