The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2012

Filed:

Apr. 03, 2009
Applicants:

Dan Yang, Hong Kong, HK;

Tao Peng, Hong Kong, HK;

Inventors:

Dan Yang, Hong Kong, HK;

Tao Peng, Hong Kong, HK;

Assignees:

Versitech Limited, Hong Kong, CN;

Morningside Ventures Limited, Hong Kong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/352 (2006.01); C07D 311/78 (2006.01); C07D 407/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein are fluorophore compounds including rhodol and rhodamine compounds which can be used as fluorescent labels and/or fluorogenic probes and methods of making same. Provided also herein are methods that can be used to track, measure, detect, or screen biological species such as protein, DNA, enzyme, antibody, organelle, cell, tissue, drug, hormone, nucleotide, nucleic acid, polysaccharide or lipid in living organisms. Specifically, the methods include the steps of contacting any of the fluorophore compounds, rhodol compounds and rhodamine compounds disclosed herein with the biological species to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening biological species.


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