The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2012
Filed:
Sep. 09, 2010
Pradip Mukerji, Gahanna, OH (US);
Tapas Das, Harbourfront, SG;
Yung-sheng Huang, Taichung, TW;
Jennifer Thurmond, Columbus, OH (US);
Suzette L. Pereira, Westerville, OH (US);
Pradip Mukerji, Gahanna, OH (US);
Tapas Das, Harbourfront, SG;
Yung-Sheng Huang, Taichung, TW;
Jennifer Thurmond, Columbus, OH (US);
Suzette L. Pereira, Westerville, OH (US);
Abbott Laboratories, Abbott Park, IL (US);
Abstract
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., 'Δ5-desaturase') and at carbon 6 (i.e., 'Δ6-desaturase') and to uses thereof. In particular, Δ5-desaturase may be utilized, for example, in the conversion of dihomo-γ-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to γ-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.