The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2012

Filed:

Mar. 30, 2009
Applicants:

Keith Bjornson, Newark, CA (US);

Harold Lee, Sunnyvale, CA (US);

Jonas Korlach, Newark, CA (US);

Stephen Turner, Menlo Park, CA (US);

Arek Bibillo, Cupertino, CA (US);

Fred Christians, Los Altos Hills, CA (US);

Robin Emig, Belmont, CA (US);

Molly He, Palo Alto, CA (US);

Insil Park, Fremont, CA (US);

Lei Jia, Palo Alto, CA (US);

Andrei Fedorov, San Mateo, CA (US);

John Lyle, Redwood Shores, CA (US);

Inventors:

Keith Bjornson, Newark, CA (US);

Harold Lee, Sunnyvale, CA (US);

Jonas Korlach, Newark, CA (US);

Stephen Turner, Menlo Park, CA (US);

Arek Bibillo, Cupertino, CA (US);

Fred Christians, Los Altos Hills, CA (US);

Robin Emig, Belmont, CA (US);

Molly He, Palo Alto, CA (US);

Insil Park, Fremont, CA (US);

Lei Jia, Palo Alto, CA (US);

Andrei Fedorov, San Mateo, CA (US);

John Lyle, Redwood Shores, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions, kits, methods and systems for nucleotide sequencing comprising producing polymerase reactions that exhibit two kinetically observable steps within an observable phase of the polymerase reaction. Two slow step systems can be produced, for example, by selecting the appropriate polymerase enzyme, polymerase reaction conditions including cofactors, and polymerase reaction substrates including the primed template and nucleotides.


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