The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
Sep. 26, 2006
Jonathan Alexander Terret, Los Altos, CA (US);
Li-sheng LU, Mountain View, CA (US);
David John King, Belmont, CA (US);
Josephine M. Cardarelli, San Carlos, CA (US);
Chin Pan, Los Altos, CA (US);
Haichun Huang, Fremont, CA (US);
Marco A. Coccia, Scotts Valley, CA (US);
Jonathan Alexander Terret, Los Altos, CA (US);
Li-sheng Lu, Mountain View, CA (US);
David John King, Belmont, CA (US);
Josephine M. Cardarelli, San Carlos, CA (US);
Chin Pan, Los Altos, CA (US);
Haichun Huang, Fremont, CA (US);
Marco A. Coccia, Scotts Valley, CA (US);
Medarex, Inc., Princeton, NJ (US);
Abstract
The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to CD70 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the disclosure are also provided. The disclosure also provides methods for treating cancer, autoimmune disease, inflammation and viral infections.