The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2012

Filed:

May. 28, 2009
Applicants:

Jeffrey Shabanowitz, Charlottesville, VA (US);

Philip D. Compton, Charlottesville, VA (US);

Lee Earley, Mountain View, CA (US);

George C. Stafford, Jr., San Jose, CA (US);

Donald F. Hunt, Charlottesville, VA (US);

Christopher Mullen, Menlo Park, CA (US);

Inventors:

Jeffrey Shabanowitz, Charlottesville, VA (US);

Philip D. Compton, Charlottesville, VA (US);

Lee Earley, Mountain View, CA (US);

George C. Stafford, Jr., San Jose, CA (US);

Donald F. Hunt, Charlottesville, VA (US);

Christopher Mullen, Menlo Park, CA (US);

Assignees:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Thermo Finnigan LLC, San Jose, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
H01J 49/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

A front-end reagent ion source for a mass spectrometer is disclosed. Reagent vapor is supplied to a reagent ionization volume located within a chamber of the mass spectrometer and maintained at a low vacuum pressure. Reagent ions are formed by interaction of the reagent vapor molecules with an electrical discharge (e.g., a glow discharge) within the ionization volume, and pass into the chamber of the mass spectrometer. At least one ion optical element located along the analyte ion path transports the reagent ions to successive chambers of the mass spectrometer. The reagent ions may be combined with the analyte ions to perform ion-ion studies such as electron transfer dissociation (ETD).


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