The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2012

Filed:

Aug. 11, 2010
Applicants:

Mark A. Ashwell, Carlisle, MA (US);

Yanbin Liu, Acton, MA (US);

Syed M. Ali, North Andover, MA (US);

Jason Hill, Auburndale, MA (US);

Woj Wrona, Waltham, MA (US);

Inventors:

Mark A. Ashwell, Carlisle, MA (US);

Yanbin Liu, Acton, MA (US);

Syed M. Ali, North Andover, MA (US);

Jason Hill, Auburndale, MA (US);

Woj Wrona, Waltham, MA (US);

Assignee:

ArQule, Inc., Woburn, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5355 (2006.01); A61K 31/5375 (2006.01); C07D 265/30 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Naphthalene-based compounds having linked heterocyclic and aromatic rings capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating conditions associated with P38 activity or cytokine activity; more particularly naphthalene-based compounds of Formula (I) having a morpholine heterocyclic ring, and methods of use thereof


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