The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Oct. 12, 2007
Hector F. Deluca, Deerfield, WI (US);
Katarzyna M. Barycka, Madison, WI (US);
Lori Plum, Arena, WI (US);
Julia Zella, Horicon, WI (US);
Margaret Clagett-dame, Deerfield, WI (US);
Hector F. DeLuca, Deerfield, WI (US);
Katarzyna M. Barycka, Madison, WI (US);
Lori Plum, Arena, WI (US);
Julia Zella, Horicon, WI (US);
Margaret Clagett-Dame, Deerfield, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
The present invention provides improved methods and compositions for therapeutically controlling and/or reducing serum phosphate levels in animals and mammalian patients. The methods comprise administering to the patient an amount of a dendrimer composition effective to prevent absorption of substantial amounts of phosphate from the patient's GI tract. In a preferred version, a dose of between 2.5 and 15 grams per day is effective to prevent over 80% of phosphate present in the patient's GI tract from being absorbed. The dendrimer composition may comprise a hydrocitrate, hydrochloride, hydrobromide, hydroacetate or hydroanionic form.