The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2012
Filed:
Mar. 18, 2005
Radiolabeled 3-[3-(benzoyl-amido)benzyloxy]aspartic acid derivative and method of producing the same
Keiko Shimamoto, Suita, JP;
Hideo Saji, Kyoto, JP;
Yuji Kuge, Kyoto, JP;
Masashi Ueda, Kyoto, JP;
Masamichi Satoh, Kyoto, JP;
Takayuki Nakagawa, Kyoto, JP;
Keiko Shimamoto, Suita, JP;
Hideo Saji, Kyoto, JP;
Yuji Kuge, Kyoto, JP;
Masashi Ueda, Kyoto, JP;
Masamichi Satoh, Kyoto, JP;
Takayuki Nakagawa, Kyoto, JP;
Suntory Holdings Limited, Osaka-shi, Osaka, JP;
Abstract
The present invention provides a radiolabeled ligand which is highly selective and potent for glutamate transporters and is usable in specifically detecting the glutamate transporter. Specifically, the present invention provides a 3-[3-(benzoylamido)benzyloxy]aspartic acid having a radioactive substituent on the benzoyl group which is represented by the following formula (1), or an ester or salt thereof: wherein X represents a substituent containing a radioactive atom(s) which is selected from a straight or branched lower aliphatic alkyl group, a hydroxyl group, a straight or branched lower aliphatic alkoxy group, an amino group, a straight or branched lower aliphatic acylamido group, a halogen atom and a straight or branched lower aliphatic haloalkyl group; and Rand Reach represents a hydrogen atom, a straight or branched lower aliphatic alkyl group or an acetoxymethyl group.