The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2011
Filed:
Oct. 15, 2009
Stephen Delcardayre, Belmont, CA (US);
Matthew B. Tobin, San Carlos, CA (US);
Willem P. C. Stemmer, Los Gatos, CA (US);
Jon E. Ness, Redwood City, CA (US);
Jeremy S. Minshull, Los Altos, CA (US);
Phillip A. Patten, Menlo Park, CA (US);
Venkiteswatan Mani Subramanian, San Diego, CA (US);
Linda A. Castle, Mountain View, CA (US);
Claus M. Krebber, Palo Alto, CA (US);
Steven H. Bass, Hillsborough, CA (US);
Ying-xin Zhang, Redwood City, CA (US);
Anthony R. Cox, Mountain View, CA (US);
Gjalt W. Huisman, San Carlos, CA (US);
Ling Yuan, El Marcero, CA (US);
Joseph A. Affholter, Zephyr Cove, CA (US);
Stephen DelCardayre, Belmont, CA (US);
Matthew B. Tobin, San Carlos, CA (US);
Willem P. C. Stemmer, Los Gatos, CA (US);
Jon E. Ness, Redwood City, CA (US);
Jeremy S. Minshull, Los Altos, CA (US);
Phillip A. Patten, Menlo Park, CA (US);
Venkiteswatan Mani Subramanian, San Diego, CA (US);
Linda A. Castle, Mountain View, CA (US);
Claus M. Krebber, Palo Alto, CA (US);
Steven H. Bass, Hillsborough, CA (US);
Ying-Xin Zhang, Redwood City, CA (US);
Anthony R. Cox, Mountain View, CA (US);
Gjalt W. Huisman, San Carlos, CA (US);
Ling Yuan, El Marcero, CA (US);
Joseph A. Affholter, Zephyr Cove, CA (US);
Codexis Mayflower Holdings, LLC, Redwood City, CA (US);
Abstract
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.