The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2011
Filed:
Oct. 02, 2008
Shu-mei Liang, Bethesda, MD (US);
Yen-po Chen, Kaohsing, TW;
Wen-bin Yang, Shenkeng Township, TW;
Chi-huey Wong, La Jolla, CA (US);
Shu-Mei Liang, Bethesda, MD (US);
Yen-Po Chen, Kaohsing, TW;
Wen-Bin Yang, Shenkeng Township, TW;
Chi-Huey Wong, La Jolla, CA (US);
Academia Sinica, Taipei, TW;
Abstract
The present disclosure relates to the discovery of methods of isolating subfractions of an F3 Reishi extract, and of administration of these novel isolates to eukaryotic cells in order to induce certain immumodulatory, hematopoeitic and tumor-inhibiting phenotypic changes in those eukaryotic cells, mediated through particular toll-like receptor (TLR) and other transmembrane receptors. F3 subfractions F301 and F331 have demonstrated that F331 is capable of activating at least TLR-2 while F301 is capable of activating at least TLR-2, TLR-4, and TLR-5.