The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2011
Filed:
Aug. 11, 2010
Masaru Mitsuda, Osaka, JP;
Tadashi Moroshima, Osaka, JP;
Kentaro Tsukuya, Osaka, JP;
Kazuhiko Watabe, Osaka, JP;
Masahiko Yamada, Osaka, JP;
Masaru Mitsuda, Osaka, JP;
Tadashi Moroshima, Osaka, JP;
Kentaro Tsukuya, Osaka, JP;
Kazuhiko Watabe, Osaka, JP;
Masahiko Yamada, Osaka, JP;
AstraZeneca AB, Sodertalje, SE;
Abstract
This invention relates to processes for the production of optically active 2-(disubstituted aryl)cyclopropylamine compounds and optically active 2-(disubstituted aryl)cyclopropane carboxamide compounds which are useful intermediates for the preparation of pharmaceutical agents, and in particular the compound [1S-(1α,2α,3β(1S*,2R*),5β)]-3-[7-[2-(3,4-difluorophenyl)-cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)-cyclopentane-1,2-diol.