The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2011
Filed:
Apr. 18, 2003
Perry J. Blackshear, Chapel Hill, NC (US);
Deborah J. Stumpo, Durham, NC (US);
Darryl C. Zeldin, Chapel Hill, NC (US);
Joan P. Graves, Raleigh, NC (US);
Perry J. Blackshear, Chapel Hill, NC (US);
Deborah J. Stumpo, Durham, NC (US);
Darryl C. Zeldin, Chapel Hill, NC (US);
Joan P. Graves, Raleigh, NC (US);
Abstract
The present disclosure relates to RFX4_v3 protein and nucleic acids encoding the RFX4_v3 protein. The present disclosure provides non-human transgenic animals with altered RFX4_v3 genes, and provides assays for the detection of RFX4_v3 and RFX4_v3 polymorphisms associated with disease states. The present disclosure additionally provides methods of determining a subjects' risk of developing congenital hydrocephalus, and treating or inhibiting its development.