The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2011

Filed:

Feb. 06, 2009
Applicants:

Micah P. Ledbetter, Oakland, CA (US);

Igor M. Savukov, Los Alamos, NM (US);

Dmitry Budker, El Cerrito, CA (US);

Vishal K. Shah, Plainsboro, NJ (US);

Svenja Knappe, Boulder, CO (US);

John Kitching, Boulder, CO (US);

David J. Michalak, Berkeley, CA (US);

Shoujun Xu, Houston, TX (US);

Alexander Pines, Berkeley, CA (US);

Inventors:

Micah P. Ledbetter, Oakland, CA (US);

Igor M. Savukov, Los Alamos, NM (US);

Dmitry Budker, El Cerrito, CA (US);

Vishal K. Shah, Plainsboro, NJ (US);

Svenja Knappe, Boulder, CO (US);

John Kitching, Boulder, CO (US);

David J. Michalak, Berkeley, CA (US);

Shoujun Xu, Houston, TX (US);

Alexander Pines, Berkeley, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01V 3/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

An integral microfluidic device includes an alkali vapor cell and microfluidic channel, which can be used to detect magnetism for nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI). Small magnetic fields in the vicinity of the vapor cell can be measured by optically polarizing and probing the spin precession in the small magnetic field. This can then be used to detect the magnetic field of in encoded analyte in the adjacent microfluidic channel. The magnetism in the microfluidic channel can be modulated by applying an appropriate series of radio or audio frequency pulses upstream from the microfluidic chip (the remote detection modality) to yield a sensitive means of detecting NMR and MRI.


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