The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2011
Filed:
Apr. 30, 2007
Yoseph Shaaltiel, Doar-Na Galil Elyon, IL;
Gideon Baum, D.N. Upper Galilee, IL;
Daniel Bartfeld, Kiryat Shmona, IL;
Sharon Hashmueli, Yesod-HaMaala, IL;
Ayala Lewkowicz, Kfar-Vradim, IL;
Yoseph Shaaltiel, Doar-Na Galil Elyon, IL;
Gideon Baum, D.N. Upper Galilee, IL;
Daniel Bartfeld, Kiryat Shmona, IL;
Sharon Hashmueli, Yesod-HaMaala, IL;
Ayala Lewkowicz, Kfar-Vradim, IL;
Protalix Ltd., Carmiel, IL;
Abstract
A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or by-passing the Golgi. The invention further relates to vectors and methods for expression and production of enzymatically active high mannose lysosomal enzymes using transgenic plant root, particularly carrot cells. More particularly, the invention relates to host cells, particularly transgenic suspended carrot cells, vectors and methods for high yield expression and production of biologically active high mannose Glucocerebrosidase (GCD). The invention further provides for compositions and methods for the treatment of lysosomal storage diseases.