The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2011
Filed:
May. 13, 2010
Neelam S. Amin, Burlingame, CA (US);
Katherine D. Collier, Los Altos, CA (US);
Melodie Estabrook, Mountain View, CA (US);
David A. Estell, San Francisco, CA (US);
Bryan P. Fox, Pacifica, CA (US);
Scott D. Power, San Bruno, CA (US);
Brian F. Schmidt, Half Moon Bay, CA (US);
Gudrun Vogtentanz, Leiden, NL;
Neelam S. Amin, Burlingame, CA (US);
Katherine D. Collier, Los Altos, CA (US);
Melodie Estabrook, Mountain View, CA (US);
David A. Estell, San Francisco, CA (US);
Bryan P. Fox, Pacifica, CA (US);
Scott D. Power, San Bruno, CA (US);
Brian F. Schmidt, Half Moon Bay, CA (US);
Gudrun Vogtentanz, Leiden, NL;
Danisco US Inc., Palo Alto, CA (US);
Abstract
The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.