The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2011
Filed:
Jul. 11, 2008
Chi-huey Wong, La Jolla, CA (US);
Alice Yu, Taipei, TW;
Ya-jen Chang, Taipei, TW;
Kun-hsien Lin, Taipei, TW;
Jung-tung Hung, Taipei, TW;
Chi-Huey Wong, La Jolla, CA (US);
Alice Yu, Taipei, TW;
Ya-Jen Chang, Taipei, TW;
Kun-Hsien Lin, Taipei, TW;
Jung-Tung Hung, Taipei, TW;
Academia Sinica, Taipei, TW;
Abstract
The present disclosure relates to synthetic alpha-galactosyl ceramide (α-GalCer) analogs, and their use as immunotherapies. In one aspect. a method of activating a cytokine response in a subject includes administering an effective amount of a compound to a subject, wherein the subject has an adaptive immune system that includes a population of cells, the population including at least one lymphocyte and at least one antigen-presenting cell, and wherein the compound is represented by the structure of formula 1: