The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2011
Filed:
Feb. 18, 2005
Masanori Takaki, Hitachinaka, JP;
Kuriko Yamada, Sapporo, JP;
Kisaburo Deguchi, Sapporo, JP;
Hiroaki Nakagawa, Sapporo, JP;
Shinichiro Nishimura, Sapporo, JP;
Masanori Takaki, Hitachinaka, JP;
Kuriko Yamada, Sapporo, JP;
Kisaburo Deguchi, Sapporo, JP;
Hiroaki Nakagawa, Sapporo, JP;
Shinichiro Nishimura, Sapporo, JP;
Hitachi High-Technologies Corporation, Tokyo, JP;
Abstract
The present invention provides a sugar chain synthesizer capable of continuously reacting sugar chains when a plurality of sugar chains are successively reacted. The sugar chain synthesizer of the present invention includes a plurality of vessels containing respective sugar nucleotide solutions, a plurality of vessels containing respective glycosyltransferases, and a reactor containing a primer that is a water-soluble polymer, into which the above described sugar nucleotide solution and glycosyltransferase are introduced. In the present invention, components in a reaction solution obtained in the reactor are separated through an ultrafiltration column, and a reaction product is then returned to the above described reactor, so as to continuously synthesize sugar chains. Although it is a complicated synthesis of sugar chains, it becomes possible to carry out such synthesis continuously and automatically.