The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2011
Filed:
Mar. 30, 2006
Chang-seok Lee, Daejeon, KR;
Jong Sung Koh, Daejeon, KR;
Ki Dong Koo, Daejeon, KR;
Geun Tae Kim, Daejeon, KR;
Kyoung-hee Kim, Daejeon, KR;
Sang Yong Hong, Daejeon, KR;
Sungsub Kim, Daejeon, KR;
Min-jung Kim, Daejeon, KR;
Hyeon Joo Yim, Daejeon, KR;
Dongchul Lim, Daejeon, KR;
Hye Jin Kim, Daejeon, KR;
Hee Oon Han, Daejeon, KR;
Seong Cheol Bu, Daejeon, KR;
OH Hwan Kwon, Daejeon, KR;
Sung Ho Kim, Daejeon, KR;
Gwong-cheung Hur, Daejeon, KR;
Ji Young Kim, Daejeon, KR;
Zi-ho Yeom, Daejeon, KR;
Dong-jun Yeo, Daejeon, KR;
Chang-Seok Lee, Daejeon, KR;
Jong Sung Koh, Daejeon, KR;
Ki Dong Koo, Daejeon, KR;
Geun Tae Kim, Daejeon, KR;
Kyoung-Hee Kim, Daejeon, KR;
Sang Yong Hong, Daejeon, KR;
Sungsub Kim, Daejeon, KR;
Min-Jung Kim, Daejeon, KR;
Hyeon Joo Yim, Daejeon, KR;
Dongchul Lim, Daejeon, KR;
Hye Jin Kim, Daejeon, KR;
Hee Oon Han, Daejeon, KR;
Seong Cheol Bu, Daejeon, KR;
Oh Hwan Kwon, Daejeon, KR;
Sung Ho Kim, Daejeon, KR;
Gwong-Cheung Hur, Daejeon, KR;
Ji Young Kim, Daejeon, KR;
Zi-Ho Yeom, Daejeon, KR;
Dong-Jun Yeo, Daejeon, KR;
LG Life Sciences, Ltd., , KR;
Abstract
Novel compounds exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV(DPP-IV) include those of the following formula (1) or pharmaceutically acceptable salt thereof: wherein A is a substituted or unsubstituted 1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridine, 5,6 -dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazine, 4,5-dihydro-7H-isooxazolo[3,4-c]pyridine, 3,4 -dihydroisoquinoline, 5,8-dihydropyrido[3,4-d]pyrimidine, or 6,7 -dihydro[1,3]thiazolo[4,5,c]pyridine, and B is a substituted or unsubstituted piperidin-2-one, morpholin-3-one, oxazolidin-2-one, pyrrolidin-2-one, or 1,5-dihydro-pyrrol-2-one. Methods of preparing the novel inhibitory compounds of formula (1) and pharmaceutical compositions containing the same as an active agent are disclosed.