The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2011
Filed:
Oct. 01, 2007
Lorraine Joan Giver, Sunnyvale, CA (US);
Lisa Marie Newman, San Jose, CA (US);
Emily Mundorff, Belmont, CA (US);
Gjalt W. Huisman, San Carlos, CA (US);
Stephane J. Jenne, Foster City, CA (US);
Jun Zhu, Sunnyvale, CA (US);
Behnaz Behrouzian, Sunnyvale, CA (US);
John H. Grate, Los Altos, CA (US);
James Lalonde, Palo Alto, CA (US);
Lorraine Joan Giver, Sunnyvale, CA (US);
Lisa Marie Newman, San Jose, CA (US);
Emily Mundorff, Belmont, CA (US);
Gjalt W. Huisman, San Carlos, CA (US);
Stephane J. Jenne, Foster City, CA (US);
Jun Zhu, Sunnyvale, CA (US);
Behnaz Behrouzian, Sunnyvale, CA (US);
John H. Grate, Los Altos, CA (US);
James Lalonde, Palo Alto, CA (US);
Codexis, Inc., Redwood City, CA (US);
Abstract
The present disclosure provides ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, method of using the engineered ketoreductase enzymes to synthesize a variety of chirally pure compounds, and the chirally pure compounds prepared therewith.