The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2011
Filed:
Apr. 15, 2005
Applicants:
Nanda Dulal Sinha, Milford, MA (US);
Satya Kuchimanchi, Milford, MA (US);
Inventors:
Nanda Dulal Sinha, Milford, MA (US);
Satya Kuchimanchi, Milford, MA (US);
Assignee:
Avecia Biotechnology, Inc., Milford, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Nitrogen-protecting groups are removed from the exocyclic nucleobase portion of a 2'-O protected nucleotide or 2′-halo nucleotide by contacting the nucleotide with an inorganic base. Typical is the removal of t-butylphenoxyacetyl protecting groups from the nucleobase portion of a 2′-O protected nucleotide on which the 2′-O protecting group is t-butyldimethylsilyl, removal or deprotection being accomplished by contact with a potassium carbonate solution.