Thrombopoetin receptor activator and process for producing the same

Abstract

A preventive, therapeutic or improving agent for diseases against which activation of the thrombopoietin receptor is effective or a platelet increasing agent, which contains a thrombopoietin receptor activator represented by the formula (1): [wherein each of Rand Ris independently a hydrogen atom, SOH, a Calkyl group, a Calkylcarbonyl group or a Carylcarbonyl group (the Calkyl group, the Calkylcarbonyl group and the Carylcarbonyl group may be optionally substituted with a halogen atom, a hydroxyl group, a Calkenyl group, a Calkoxy group, a Calkoxycarbonyl group, a Caryl group, a 2-pyridyl group, a 3-pyridyl group, a 4-pyridyl group, a 2-furanyl group, a 3-furanyl group, a 2-thienyl group, a 3-thienyl group or NRR) , and each of R, Rand Ris independently a hydrogen atom, a hydroxyl group or a Calkoxy group].