The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2010

Filed:

Oct. 09, 2009
Applicants:

Anthony Frank Kreft, Langhorne, PA (US);

Derek Cecil Cole, New City, NY (US);

Kevin R. Woller, Ayer, MA (US);

Joseph Raymond Stock, Monroe, NY (US);

George Diamantidis, Randolph, NJ (US);

Dennis Michael Kubrak, Philadelphia, PA (US);

Kristina Martha Kutterer, Westwood, NJ (US);

William J. Moore, Collegeville, PA (US);

David S. Casebier, Carlisle, MA (US);

Inventors:

Anthony Frank Kreft, Langhorne, PA (US);

Derek Cecil Cole, New City, NY (US);

Kevin R. Woller, Ayer, MA (US);

Joseph Raymond Stock, Monroe, NY (US);

George Diamantidis, Randolph, NJ (US);

Dennis Michael Kubrak, Philadelphia, PA (US);

Kristina Martha Kutterer, Westwood, NJ (US);

William J. Moore, Collegeville, PA (US);

David S. Casebier, Carlisle, MA (US);

Assignees:

Wyeth LLC, Madison, NJ (US);

ArQule, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/381 (2006.01); C07D 333/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula (I), wherein R, R, R, R, R, R, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer's disease and Down's syndrome are described.


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