The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Sep. 15, 2003
Jennifer Jones Mcintire, Palo Alto, CA (US);
Rosemarie Dekruyff, Newton, MA (US);
Dale T. Umetsu, Newton, MA (US);
Gordon Freeman, Boston, MA (US);
Jennifer Jones McIntire, Palo Alto, CA (US);
Rosemarie Dekruyff, Newton, MA (US);
Dale T. Umetsu, Newton, MA (US);
Gordon Freeman, Boston, MA (US);
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Dana-Farber Cancer Institute, Boston, MA (US);
Abstract
A genetic locus and corresponding family of proteins associated with regulation of immune development, function, and cell survival are provided. The locus comprising the TIM family is genetically associated with immune dysfunction, including atopy, autoimmunity, inflammatory bowel disease, dysplasia, and susceptibility to blood-bourne infectious diseases. Polymorphisms in the human TIM-1 gene and exposure to Hepatitis A Virus (HAV) are shown to be associated with protection from the development of atopy.