The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2010

Filed:

Apr. 30, 2003
Applicants:

Chandra Vargeese, Broomfield, CO (US);

Peter Haeberli, Berthoud, CO (US);

Weimin Wang, Superior, CO (US);

Tongqian Chen, Longmont, CO (US);

Inventors:

Chandra Vargeese, Broomfield, CO (US);

Peter Haeberli, Berthoud, CO (US);

Weimin Wang, Superior, CO (US);

Tongqian Chen, Longmont, CO (US);

Assignee:

Merck Sharpe & Dohme, Rahway, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/6615 (2006.01); A61K 31/7115 (2006.01); A61K 31/713 (2006.01); C07F 9/09 (2006.01); C07F 9/165 (2006.01); C07H 21/02 (2006.01); A61K 31/711 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention features conjugates, degradable linkers, compositions, methods of synthesis, and applications thereof, including cholesterol derived conjugates of biologically active compounds, including antibodies, antivirals, chemotherapeutics, peptides, proteins, hormones, nucleosides, nucleotides, non-nucleosides, and nucleic acids including enzymatic nucleic acids, DNAzymes, allozymes, antisense, dsRNA, siNA, siRNA, triplex oligonucleotides, 2,5-A chimeras, decoys and aptamers.


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