The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2010
Filed:
Aug. 31, 2007
David A. Flockhart, Indianapolis, IN (US);
Zeruesenay Desta, Carmel, IN (US);
Anil S. Modak, Haverhill, MA (US);
Yasuhisa Kurogi, North Andover, MA (US);
David A. Flockhart, Indianapolis, IN (US);
Zeruesenay Desta, Carmel, IN (US);
Anil S. Modak, Haverhill, MA (US);
Yasuhisa Kurogi, North Andover, MA (US);
Cambridge Isotope Laboratories, Inc., Andover, MA (US);
Abstract
The present invention relates, generally to a method of determining and assessing cytochrome P450 2C19-related (CYP2Cl9) metabolic capacity in an individual mammalian subject via a breath assay, by determining the relative amount ofCOexhaled by the subject upon intravenous or oral administration of aC-labeled CYP2C19 substrate compound. The present invention is useful as a non-invasive, in vivo assay for evaluating CYP2C19 enzyme activity in a subject using the metaboliteCOin expired breath, to phenotype individual subjects and to determine the selection, optimal dosage and timing of drug administration.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile