The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2010
Filed:
Aug. 20, 2007
Akira Inoue, Yokohama, JP;
Hitoshi Hatayama, Yokohama, JP;
Hiroshi Suganuma, Tokyo, JP;
Kunio Awazu, Nishinomiya, JP;
Toshihiro Kushibiki, Ibaraki, JP;
Akira Inoue, Yokohama, JP;
Hitoshi Hatayama, Yokohama, JP;
Hiroshi Suganuma, Tokyo, JP;
Kunio Awazu, Nishinomiya, JP;
Toshihiro Kushibiki, Ibaraki, JP;
Sumitomo Electric Industries, Ltd., Osaka, JP;
Abstract
The invention offers a technique that selectively differentiation-induces mesenchymal stem cells, which can differentiate to cells that constitute various tissues and organs, to osteoblasts. In addition, the invention offers a technique that differentiation-induces mesenchymal stem cells to osteoblasts with a simple operation that needs only short time and that is noninvasive. The inventors have found that the switch for the differentiation induction to osteoblasts is turned on by translocating biological clock-relevant factors existing in mesenchymal stem cells from the cells' cytoplasm to the cells' nucleus. The inventors have also found that the switch can be turned on by irradiating the cells for a short time with a lightwave having a specific wavelength that is noninvasive.