The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
May. 02, 2007
Stephen F. Badylak, W. Lafayette, IN (US);
Jeffrey Bonadio, Ann Arbor, MI (US);
Sherry Voytik, Lafayette, IN (US);
Stephen F. Badylak, W. Lafayette, IN (US);
Jeffrey Bonadio, Ann Arbor, MI (US);
Sherry Voytik, Lafayette, IN (US);
Purdue Research Foundation, West Lafayette, IN (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
Clarian Health Partners, Inc., Indianapolis, IN (US);
Abstract
A composition useful for the production of transformed eukaryotic cells is described. The composition comprises submucosal tissue and a nucleic acid sequence. The nucleic acid sequence is typically recombinant DNA including gene(s) encoding for one or more biofunctional proteins. The submucosal tissue component of the present composition comprises the tunica submucosa of vertebrate intestine delaminated from the tunica muscularis and at least the luminal portion of the tunica mucosa. Injection or implantation of the composition into a host induces the formation of transformed cells capable of expressing gene(s) encoded by the nucleic acid sequence.