The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 2010
Filed:
Jan. 25, 2010
Qiong Cheng, Wilmington, DE (US);
Linda Jane Decarolis, Wilmington, DE (US);
Stephen R. Fahnestock, Wilmington, DE (US);
Tanja Maria Gruber, Media, PA (US);
Lisa Diane Reiss, Wilmington, DE (US);
Pierre E. Rouviere, Wilmington, DE (US);
Qiong Cheng, Wilmington, DE (US);
Linda Jane Decarolis, Wilmington, DE (US);
Stephen R. Fahnestock, Wilmington, DE (US);
Tanja Maria Gruber, Media, PA (US);
Lisa Diane Reiss, Wilmington, DE (US);
Pierre E. Rouviere, Wilmington, DE (US);
E.I. du Pont de Nemours and Company, Wilmington, DE (US);
Abstract
Peptide tags, referred to here as inclusion body tags, are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.