The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 17, 2010

Filed:

Aug. 28, 2008
Applicants:

David T. Scadden, Weston, MA (US);

Laura M. Calvi, Rochester, NY (US);

Gregor Adams, Boston, MA (US);

Henry M. Kronenberg, Belmont, MA (US);

Inventors:

David T. Scadden, Weston, MA (US);

Laura M. Calvi, Rochester, NY (US);

Gregor Adams, Boston, MA (US);

Henry M. Kronenberg, Belmont, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/38 (2006.01); A61K 35/26 (2006.01); C12N 5/08 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to methods for manipulating hematopoietic progenitor cells and related products. In one aspect the invention relates to the use of agents that activate a PTH/PTHrP receptor to enhance the growth and maintenance of hematopoietic progenitor cells in vivo and in vitro, to enhance mobilization of hematopoietic stem cells, to improve the efficiency of targeting cells to the bone marrow, and/or to modulate hematopoietic progenitor cell function.


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