The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 2010
Filed:
Oct. 22, 2007
Frank Mercurio, San Diego, CA (US);
Hengyi Zhu, San Diego, CA (US);
Miguel Barbosa, San Diego, CA (US);
Jian Wu LI, San Diego, CA (US);
Brion W. Murray, San Diego, CA (US);
Frank Mercurio, San Diego, CA (US);
Hengyi Zhu, San Diego, CA (US);
Miguel Barbosa, San Diego, CA (US);
Jian Wu Li, San Diego, CA (US);
Brion W. Murray, San Diego, CA (US);
Signal Pharmaceuticals, San Diego, CA (US);
Abstract
Compositions and methods are provided for treating NF-κB-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-κB cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-κB activation.