The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2010
Filed:
Jul. 26, 2005
Yoshiaki Isshiki, Kanagawa, JP;
Yasunori Kohchi, Kanagawa, JP;
Eisaku Mizuguchi, Kanagawa, JP;
Hitoshi Iikura, Kanagawa, JP;
Yasuaki Matsubara, Kanagawa, JP;
Shinji Tsujii, Kanagawa, JP;
Nobuo Shimma, Kanagawa, JP;
Masanori Miwa, Kanagawa, JP;
Satoshi Aida, Kanagawa, JP;
Masami Kohchi, Kanagawa, JP;
Takeshi Murata, Kanagawa, JP;
Kosuke Aso, Kanagawa, JP;
Yoshiaki Isshiki, Kanagawa, JP;
Yasunori Kohchi, Kanagawa, JP;
Eisaku Mizuguchi, Kanagawa, JP;
Hitoshi Iikura, Kanagawa, JP;
Yasuaki Matsubara, Kanagawa, JP;
Shinji Tsujii, Kanagawa, JP;
Nobuo Shimma, Kanagawa, JP;
Masanori Miwa, Kanagawa, JP;
Satoshi Aida, Kanagawa, JP;
Masami Kohchi, Kanagawa, JP;
Takeshi Murata, Kanagawa, JP;
Kosuke Aso, Kanagawa, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
An objective of the present invention is to provide compounds that exhibit strong MEK-inhibiting activity and are stable in vivo and soluble in water, which can be used as preventive or therapeutic agents for proliferative diseases. The compounds of the present invention and pharmaceutically acceptable salts thereof are represented by the following formula (1): [where R, R, R, R, and X are the same as defined in the present patent application].