The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2010
Filed:
Mar. 02, 2004
Fred R. Kramer, Riverdale, NY (US);
Sanjay Tyagi, New York, NY (US);
Salvatore A. E. Marras, Jersey City, NJ (US);
Hiyam Elhajj Trunfio, New York, NY (US);
Fred R. Kramer, Riverdale, NY (US);
Sanjay Tyagi, New York, NY (US);
Salvatore A. E. Marras, Jersey City, NJ (US);
Hiyam Elhajj Trunfio, New York, NY (US);
The Public Health Research Institute of the City of New York, Newark, NJ (US);
Abstract
A coding scheme for microcarriers suitable for use in distributed arrays includes labeling the carriers with quenched signaling hairpin molecules with any one of three to eight distinguishable fluorophores wherein the hairpins are of at least two types, most preferably three types, that open and fluoresce differentially as a chemical or physical condition, for example temperature, is changed. Mixtures of microcarriers having immobilized capture probes can be decoded by measuring fluorescence from said fluorophores under conditions under which only one type of hairpin is open, under which two types of hairpin are open, and so on. Mixtures of coded microcarriers with capture probes are used in assays for nucleic acids utilizing microarray methods.