The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 2010

Filed:

May. 16, 2001
Applicants:

David Beach, Boston, MA (US);

Emily Bernstein, Huntington, NY (US);

Amy Caudy, Melville, NY (US);

Scott Hammond, Huntington, NY (US);

Gregory Hannon, Huntington, NY (US);

Inventors:

David Beach, Boston, MA (US);

Emily Bernstein, Huntington, NY (US);

Amy Caudy, Melville, NY (US);

Scott Hammond, Huntington, NY (US);

Gregory Hannon, Huntington, NY (US);

Assignee:

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods for attenuating gene expression in a cell using gene-targeted double stranded RNA (dsRNA). The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the 'target' gene).


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