The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Aug. 24, 2006
Roger L. Kaspar, Santa Cruz, CA (US);
Robyn P. Hickerson, Santa Cruz, CA (US);
Frances J. D. Smith, Dundee, GB;
W. H. Irwin Mclean, Perthshire, GB;
Roger L. Kaspar, Santa Cruz, CA (US);
Robyn P. Hickerson, Santa Cruz, CA (US);
Frances J. D. Smith, Dundee, GB;
W. H. Irwin McLean, Perthshire, GB;
Transderm, Inc., Salt Lake City, UT (US);
Abstract
A method for treating pachyonychia congenita (PC) by identifying a genetic mutation contributing to PC, preparing a siRNA sequence that inhibits expression of the identified mutation, and administering the siRNA to a cell of a subject afflicted with PC. The siRNA treatment can include silencing of both the mutated and associated wildtype genes for a specific keratin. Specific mutations and inhibitory sequences are identified.