The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
Feb. 09, 2006
Chiang J. LI, West Roxbury, MA (US);
Mark A. Ashwell, Carlisle, MA (US);
Jason Hill, Auburndale, MA (US);
Magdi M. Moussa, Malden, MA (US);
Neru Munshi, Burlington, MA (US);
Chiang J. Li, West Roxbury, MA (US);
Mark A. Ashwell, Carlisle, MA (US);
Jason Hill, Auburndale, MA (US);
Magdi M. Moussa, Malden, MA (US);
Neru Munshi, Burlington, MA (US);
ArQule, Inc., Woburn, MA (US);
Abstract
The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention.