The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2010
Filed:
Jul. 30, 2004
Dominique Bourel, La Madeleine, FR;
Sylvie Jorieux, Villeneuve d'Ascq, FR;
Christophe DE Romeuf, Lambersart, FR;
Philippe Klein, Lille, FR;
Christine Gaucher, Sequedin, FR;
Nicolas Bihoreau, Orsay, FR;
Emmanuel Nony, Antony, FR;
Dominique Bourel, La Madeleine, FR;
Sylvie Jorieux, Villeneuve d'Ascq, FR;
Christophe De Romeuf, Lambersart, FR;
Philippe Klein, Lille, FR;
Christine Gaucher, Sequedin, FR;
Nicolas Bihoreau, Orsay, FR;
Emmanuel Nony, Antony, FR;
Abstract
The invention concerns the use of human or humanized chimeric monoclonal antibodies which are produced in selected cell lines, said antibodies bringing about a high ADCC activity as well as a high secretion of cytokines and interleukins, for treating underpopulations of so-called weak-response patients exhibiting CD16 FCGR3A-158F homozygote or FCGR3A-158V/F heterozygote polymorphism.