The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2010
Filed:
Jan. 16, 2004
Mylavarapu Venkatramesh, Ballwin, MO (US);
David R. Corbin, Chesterfield, MO (US);
B. Ganesh Bhat, St. Louis, MO (US);
Sekhar S. Boddupalli, San Jose, CA (US);
Robert J. Grebenok, East Amherst, NY (US);
Ganesh M. Kishore, Creve Coeur, MO (US);
Kathryn D. Lardizabal, Woodland, CA (US);
Michael W. Lassner, Foster City, CA (US);
Shaukat H. Rangwala, Chesterfield, MO (US);
Balasulojini Karunanandaa, Creve Coeur, MO (US);
Mylavarapu Venkatramesh, Ballwin, MO (US);
David R. Corbin, Chesterfield, MO (US);
B. Ganesh Bhat, St. Louis, MO (US);
Sekhar S. Boddupalli, San Jose, CA (US);
Robert J. Grebenok, East Amherst, NY (US);
Ganesh M. Kishore, Creve Coeur, MO (US);
Kathryn D. Lardizabal, Woodland, CA (US);
Michael W. Lassner, Foster City, CA (US);
Shaukat H. Rangwala, Chesterfield, MO (US);
Balasulojini Karunanandaa, Creve Coeur, MO (US);
Monsanto Technology LLC, St. Louis, MO (US);
Abstract
Provided are recombinant constructs comprising DNA sequences encoding enzymes effective in altering the biosynthesis and accumulation of sterol compounds and tocopherols in transgenic plants. Also provided are methods of using such constructs to produce transgenic plants, seeds of which contain elevated levels of sitostanol and/or sitostanol esters, and α-tocopherol, as well as reduced levels of campesterol and campestanol and their corresponding esters. These seeds also contain the novel sterol brassicastanol. Oil obtained from seeds of such transgenic plants is also provided. This oil can be used to prepare food and pharmaceutical compositions effective in lowering the level of low density lipoprotein cholesterol in blood serum. In addition, novel DNA sequences encoding plant steroid 5α-reductases are also disclosed.