The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2010
Filed:
Mar. 12, 2001
Naoshi Fukushima, Gotemba, JP;
Masayuki Tsuchiya, Gotemba, JP;
Masayoshi Oh-eda, Gotemba, JP;
Shinsuke Uno, Gotemba, JP;
Yasufumi Kikuchi, Gotemba, JP;
Naoshi Fukushima, Gotemba, JP;
Masayuki Tsuchiya, Gotemba, JP;
Masayoshi Oh-Eda, Gotemba, JP;
Shinsuke Uno, Gotemba, JP;
Yasufumi Kikuchi, Gotemba, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
This invention relates to reconstructed polypeptides which have properties of inducing apoptosis of nucleated blood cells having Integrin Associated Protein (IAP) and causing no hemagglutination. The reconstructed polypeptides comprise two or more H chain V regions and two or more L chain V regions of a monoclonal antibody which induces apoptosis of nucleated blood cells having IAP. The reconstructed polypeptides are useful as a therapeutic agent for blood dyscrasia such as leukemia.