The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2010
Filed:
Jan. 09, 2007
Arthur G. Taveras, Southborough, MA (US);
Jianhua Chao, Pompton Lakes, NJ (US);
Purakkattle J. Biju, Piscataway, NJ (US);
Younong Yu, East Brunswick, NJ (US);
Cynthia J. Aki, Livingston, NJ (US);
J. Robert Merritt, Ewing, NJ (US);
GE LI, Shanghai, CN;
John J. Baldwin, Gwynedd Valley, PA (US);
Gaifa Lai, Monmouth Junction, NJ (US);
Minglang Wu, Monmouth Junction, NJ (US);
Evan A. Hecker, Austin, TX (US);
Arthur G. Taveras, Southborough, MA (US);
Jianhua Chao, Pompton Lakes, NJ (US);
Purakkattle J. Biju, Piscataway, NJ (US);
Younong Yu, East Brunswick, NJ (US);
Cynthia J. Aki, Livingston, NJ (US);
J. Robert Merritt, Ewing, NJ (US);
Ge Li, Shanghai, CN;
John J. Baldwin, Gwynedd Valley, PA (US);
Gaifa Lai, Monmouth Junction, NJ (US);
Minglang Wu, Monmouth Junction, NJ (US);
Evan A. Hecker, Austin, TX (US);
Schering Corporation, Kenilworth, NJ (US);
Pharmacopeia, Inc., Cranbury, NJ (US);
Abstract
Disclosed are novel compounds of the formula: and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula IA.