The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2010

Filed:

Sep. 27, 2006
Applicants:

Anthony Frank Kreft, Langhorne, PA (US);

Derek Cecil Cole, New City, NY (US);

Kevin Roger Woller, Ayer, MA (US);

Joseph Raymond Stock, Monroe, NY (US);

Kristina Martha Kutterer, Westwood, NJ (US);

Dennis Martin Kubrak, Philadelphia, PA (US);

Charles William Mann, North Wales, PA (US);

William Jay Moore, Collegewille, PA (US);

David Scott Casebier, Carlisle, MA (US);

Inventors:

Anthony Frank Kreft, Langhorne, PA (US);

Derek Cecil Cole, New City, NY (US);

Kevin Roger Woller, Ayer, MA (US);

Joseph Raymond Stock, Monroe, NY (US);

Kristina Martha Kutterer, Westwood, NJ (US);

Dennis Martin Kubrak, Philadelphia, PA (US);

Charles William Mann, North Wales, PA (US);

William Jay Moore, Collegewille, PA (US);

David Scott Casebier, Carlisle, MA (US);

Assignees:

Wyeth, Madison, NJ (US);

ArQule, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/18 (2006.01); A61K 31/34 (2006.01); A61K 31/357 (2006.01); A61K 31/4245 (2006.01); C07C 311/17 (2006.01); C07D 209/14 (2006.01); C07D 271/12 (2006.01); C07D 307/52 (2006.01); C07D 317/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula I, wherein R-Rare defined herein are provided, together with pharmaceutically acceptable salts, hydrates, metabolites, and/or prodrugs thereof. Uses of these compounds for inhibiting beta amyloid production and for the prevention and treatment of Alzheimer's Disease and Down's syndrome are also described.


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