The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2010
Filed:
Mar. 29, 2005
Osamu Ohara, Kisarazu, JP;
Takahiro Nagase, Kisarazu, JP;
Michio Oishi, Kisarazu, JP;
Hiroshi Yokota, Tokyo, JP;
Osamu Kamida, Tokyo, JP;
Osamu Ohara, Kisarazu, JP;
Takahiro Nagase, Kisarazu, JP;
Michio Oishi, Kisarazu, JP;
Hiroshi Yokota, Tokyo, JP;
Osamu Kamida, Tokyo, JP;
Daiichi Sankyo Company, Limited, Tokyo, JP;
Kazusa DNA Research Institute Foundation, Chiba, JP;
Abstract
A gene encoding a novel protein that works as a guanine nucleotide exchange factor (GEF) for a Rho family protein being one group of small GTP-binding proteins, namely, a polynucleotide shown by the nucleotide sequence set forth in SEQ ID NO: 1, SEQ ID NO: 3, or SEQ ID NO: 5, or the complementary strand, the equivalents of the polynucleotide, a protein encoded by the polynucleotide, a vector containing the polynucleotide, a transformant containing the vector, an antibody against the protein encoded by the polynucleotide, a method of identifying a compound that inhibits the function of the protein encoded by the polynucleotide and/or the expression of the polynucleotide, a method of determining a disease, a pharmaceutical composition, and a reagent kit are provided.