The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2010
Filed:
Mar. 18, 2004
John Mccafferty, Sawston, GB;
Anthony Richard Pope, Cambridge, GB;
Kevin Stuart Johnson, Cambridge, GB;
Henricus Renerus Jacobus Mattheus Hoogenboom, Little Shalford, GB;
Andrew David Griffiths, Cambridge, GB;
Ronald Henry Jackson, Cambridge, GB;
Kaspar Philipp Holliger, Cambridge, GB;
James David Marks, Cherry Hinton, GB;
Timothy Piers Clackson, Palo Alto, CA (US);
David John Chiswell, Middle Claydon, GB;
Gregory Paul Winter, Cambridge, GB;
Timothy Peter Bonnert, Cambridge, GB;
John McCafferty, Sawston, GB;
Anthony Richard Pope, Cambridge, GB;
Kevin Stuart Johnson, Cambridge, GB;
Henricus Renerus Jacobus Mattheus Hoogenboom, Little Shalford, GB;
Andrew David Griffiths, Cambridge, GB;
Ronald Henry Jackson, Cambridge, GB;
Kaspar Philipp Holliger, Cambridge, GB;
James David Marks, Cherry Hinton, GB;
Timothy Piers Clackson, Palo Alto, CA (US);
David John Chiswell, Middle Claydon, GB;
Gregory Paul Winter, Cambridge, GB;
Timothy Peter Bonnert, Cambridge, GB;
Medical Research Council, London, GB;
Medimmune Limited, Cambridge, GB;
Abstract
A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recombinant genetic display package (rgdp) containing DNA encoding the sbp member or a polypeptide component thereof, by virtue of the sbp member or a polypeptide component thereof being expressed as a fusion with a capsid component of the rgdp. The displayed sbps may be selected by affinity with a complementary sbp member, and the DNA recovered from selected rgdps for expression of the selected sbp members. A phagemid may be used as an expression vector, with said capsid fusion helping to package the phagemid DNA.