The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2010
Filed:
May. 26, 2006
Marta C. Abad, Downingtown, PA (US);
Dionisios Rentzeperis, Downingtown, PA (US);
John O'neill, Downingtown, PA (US);
Hossein B. Askari, Exton, PA (US);
Cynthia M. Milligan, Exton, PA (US);
Frank A. Lewandowski, Exton, PA (US);
Marta C. Abad, Downingtown, PA (US);
Dionisios Rentzeperis, Downingtown, PA (US);
John O'Neill, Downingtown, PA (US);
Hossein B. Askari, Exton, PA (US);
Cynthia M. Milligan, Exton, PA (US);
Frank A. Lewandowski, Exton, PA (US);
Johnson & Johnson Pharmaceutical Research & Development, LLC, New Brunswick, NJ (US);
Abstract
A method for the identification of novel compounds that interact and stabilize the ligand binding domain of estrogen-related receptor gamma (ERRγ), a methodology for producing diffraction quality crystal structures in the presence of antagonist and agonist ligands, including Bisphenol A, and the identification of novel biologically-active compounds that have an effect on the transcriptional-activating activity of ERRγ are disclosed.