The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2009
Filed:
May. 26, 2004
Peter Kufer, Moosburg, DE;
Ralf Lutterbuse, Munich, DE;
Birgit Kohleisen, Munich, DE;
Steven Zeman, Munich, DE;
Patrick Bauerle, Gauting, DE;
Peter Kufer, Moosburg, DE;
Ralf Lutterbuse, Munich, DE;
Birgit Kohleisen, Munich, DE;
Steven Zeman, Munich, DE;
Patrick Bauerle, Gauting, DE;
Micromet AG, Munchen, DE;
Abstract
The present invention relates to a pharmaceutical composition comprising a bispecific single chain antibody construct comprising binding domains specific for human CD3 and human CD19, wherein the corresponding variable heavy chain regions (V) and the corresponding variable light chain regions (V) regions are arranged, from N-terminus to C-terminus, in the order V(CD19)-V(CD19)-V(CD3)-V(CD3) or V(CD3)-V-(CD3)-V(CD19)-V(CD19). Processes for the production of the pharmaceutical compositions and medical/pharmaceutical uses for the specific bispecific single chain antibody molecules bearing specificities for the human CD3 antigen and the human CD19 antigen are also disclosed.