The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2009
Filed:
Apr. 23, 2009
Tiruvettipuram K. Thiruvengadam, Kendall Park, NJ (US);
Tao Wang, Sprinfield, NJ (US);
Jing Liao, Livingston, NJ (US);
John S. Chiu, Parsippany, NJ (US);
David J. S. Tsai, Warren, NJ (US);
Hong-chang Lee, Livingston, NJ (US);
Wenxue Wu, Princeton Junction, NJ (US);
Xiaoyong Fu, Edison, NJ (US);
Tiruvettipuram K. Thiruvengadam, Kendall Park, NJ (US);
Tao Wang, Sprinfield, NJ (US);
Jing Liao, Livingston, NJ (US);
John S. Chiu, Parsippany, NJ (US);
David J. S. Tsai, Warren, NJ (US);
Hong-Chang Lee, Livingston, NJ (US);
Wenxue Wu, Princeton Junction, NJ (US);
Xiaoyong Fu, Edison, NJ (US);
Schering Corporation, Kenilworth, NJ (US);
Abstract
The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield on the desired enantiomer. An example of a step in the synthesis of such a himbacine analog is as follows: