The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2009
Filed:
Jul. 30, 2008
José L. Boyer, Chapel Hill, NC (US);
James G. Douglass, Iii, Apex, NC (US);
Sammy R. Shaver, Chapel Hill, NC (US);
José L. Boyer, Chapel Hill, NC (US);
James G. Douglass, III, Apex, NC (US);
Sammy R. Shaver, Chapel Hill, NC (US);
Inspire Pharmaceuticals, Inc., Durham, NC (US);
University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
The present invention provides a P2Yreceptor antagonist compound-eluting stent, wherein the stent is coated with one or more P2Yreceptor antagonist compounds or a pharmaceutically acceptable salt, solvate, or hydrate thereof. When the stent is placed in a narrowed or damaged arterial vessel, a therapeutically effective amount of the P2Yreceptor antagonist compound is eluted continuously from the stent to the local environment of the stent. The P2Yreceptor antagonist compound-eluting stents are useful in preventing thrombosis and restenosis, and are effective in inhibiting the contraction of vascular smooth muscle cells, inhibiting cell proliferation, and reducing inflammation.