The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2009
Filed:
Nov. 21, 2002
Fred Ramsdell, Bainbridge Island, WA (US);
Sean C. Proll, Seattle, WA (US);
Karen Staehling-hampton, Bothell, WA (US);
Mark W. Appleby, Shoreline, WA (US);
Leon Fernando Garcia-martinez, Woodinville, WA (US);
Fred Ramsdell, Bainbridge Island, WA (US);
Sean C. Proll, Seattle, WA (US);
Karen Staehling-Hampton, Bothell, WA (US);
Mark W. Appleby, Shoreline, WA (US);
Leon Fernando Garcia-Martinez, Woodinville, WA (US);
Celltech R&D, Inc., Bothell, WA (US);
Abstract
The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.