The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2009
Filed:
Apr. 16, 2003
Applicants:
Rosanne M. Crooke, Carlsbad, CA (US);
Mark J. Graham, San Clem, CA (US);
Kristina M. Lemonidis, Temecula, CA (US);
Kenneth W. Dobie, Del Mar, CA (US);
Inventors:
Rosanne M. Crooke, Carlsbad, CA (US);
Mark J. Graham, San Clem, CA (US);
Kristina M. Lemonidis, Temecula, CA (US);
Kenneth W. Dobie, Del Mar, CA (US);
Assignee:
Isis Pharmaceuticals Inc., Carlsbad, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided.