The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2009
Filed:
Nov. 24, 2004
Applicants:
Barton Holmquist, Eagle, NE (US);
Daniel Strydom, Lincoln, NE (US);
Jin Seog Seo, Brampton, CA;
Kirk Cryer, Madison, WI (US);
Inventors:
Barton Holmquist, Eagle, NE (US);
Daniel Strydom, Lincoln, NE (US);
Jin Seog Seo, Brampton, CA;
Kirk Cryer, Madison, WI (US);
Assignee:
Restoragen, Inc., Lincoln, NE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08H 1/00 (2006.01); C12N 1/20 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides a palladium-promoted hydrolytic polypeptide cleavage process which selectively cleaves the polypeptide at a Cys-His cleavage site comprising solubilizing the polypeptide in a reaction mixture comprised of a palladium promoter dissolved in a high-concentration formic acid, wherein the concentration of the formic acid in the reaction mixture is between about 1 to about 22 molar.